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KMID : 0605319950070020183
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Journal of Sasang Constitutional Medicine
1995 Volume.7 No. 2 p.183 ~ p.212
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Influence of Taeumin and Soumin Prescriptions on the Activity of Autonomic Nervous System in Rats Received Stress
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Abstract
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In order to investigate the influence of four Sasang prescriptions, Sou(?)min P´almunjat´ang(SPG), Sou(?)min Shibimikwanjungt´ang(SSK), T´aeu(?)min Chowisu(?)ngch´o(?)ngt´ang(TCS), and T´aeu(?)min Ch´o(?)ngp´yesagant´ang(TCR), on the activity of the autonomic nervous system in the rats exposed to noise and vibration stress, the contents of catecholamines in the urine, body temperature, heart rate, blood pressure, and stomach mucosa change were checked in this experiment.
The results obtained were as follows;
1. On the 7th and 12th days from the beginning, the experimental indexes of the controled group were increased more than those of the normal group, and it meant that the noise and vibration stress induced an autonomic nervous system disorder in rats.
2. The urine-epinephrine contents in all experimental groups were decreased more than in the controled group, and in the Tcs and the Tcp groups those were significantly decreased on the 7th and 12th days.
3. The urine-norepinephrine contents in the SPK, TCS, and the TCP groups were significantly decreased on the 7th day, and in the TCS and the SPG groupsthose were significantly decredsed on the 12th day.
4. The urine-dopamine contents in the TCS group were significantlly decreased on the 12th day.
5. The body temperaature was decreased significantly in the SPG and the SSK groups on the 7th day.
6. The heart rate was significantly decreased in the SPG group in the 7th day, and it was decreased significantly in the SPG and the SSK groups on the 12th day.
7. The blood pressure was decreased in ghe SPG group significantly on the 7th day.
8. The stomach mucosa remarkably recovered from gastric ulcers in the SPG group and significantly recorvered in the other groups on the 7th day.
From the above findings, th could be assumed that T´aeumin and Soumin prescriptions had some significant influence on the control of the autonomic nervous system in the rats that recieved stress.
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